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1

Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte dna repair assay

Dr. Jon C. Mirsalis, C. Kim Tyson, Byron E. Butterworth

Journal:

Environmental and Molecular Mutagenesis

Year:

1982

Language:

english

File:

PDF, 548 KB

english, 1982

2

Unscheduled DNA synthesis in rat tracheal epithelial cells, hepatocytes and spermatocytes following exposure to methyl chloride in vitro and in vivo

Peter K. Working, David J. Doolittle, Tracey Smith-Oliver, Russell D. White, Byron E. Butterworth

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1986

Language:

english

File:

PDF, 510 KB

english, 1986

3

Use of in Vivo/In Vitro Unscheduled Dna Synthesis for Identification of Organ-Specific Carcinogens

Furihata, Chie, Matsushima, Taijiro, Butterworth, Byron E.

Journal:

Critical Reviews in Toxicology

Year:

1987

Language:

english

File:

PDF, 1.75 MB

english, 1987

4

Measurement of genotoxic activity in multiple tissues following inhalation exposure to dimethylnitrosamine

David J. Doolittle, Edilberto Bermudez, Peter K. Working, Byron E. Butterworth

Journal:

Mutation Research Letters

Year:

1984

Language:

english

File:

PDF, 352 KB

english, 1984

5

Science-based risk assessments for drinking water disinfection by-products

Byron E. Butterworth

Journal:

Environmental Research

Year:

2005

Language:

english

File:

PDF, 162 KB

english, 2005

6

Chloroform-induced cytotoxicity and regenerative cell proliferation in the kidneys and liver of BDF1 mice

Michael V. Templin, Keith C. Jamison, Catherine S. Sprankle, Douglas C. Wolf, Brian A. Wong, Byron E. Butterworth

Journal:

Year:

1996

Language:

english

File:

PDF, 856 KB

english, 1996

7

Supplement 5: Cell Proliferation and Chemical Carcinogenesis || Concepts, Labeling Procedures, and Design of Cell Proliferation Studies Relating to Carcinogenesis

Thomas L. Goldsworthy, Byron E. Butterworth and Robert R. Maronpot

Journal:

Environmental Health Perspectives

Year:

1993

Language:

english

File:

PDF, 1.51 MB

english, 1993

8

Induction of unscheduled DNA synthesis in rat hepatocytes following in vivo treatment with dinitrotoluene

Mirsalis, Jon C., Butterworth, Byron E.

Journal:

Year:

1982

Language:

english

File:

PDF, 494 KB

english, 1982

9

Induction of DNA repair in rat spermatocytes and hepatocytes by 1,2-dibromoethane: the role of glutathione conjugation

Working, Peter K., Smith-Oliver, Tracey, White, Russell D., Butterworth, Byron E.

Journal:

Year:

1986

Language:

english

File:

PDF, 2.01 MB

english, 1986

10

Evaluation of the genotoxic potential of glutaraldehyde

Mary Beth G. St. Clair, Edilberto Bermudez, Elizabeth A. Gross, Byron E. Butterworth, Dr. Leslie Recio, A. V. Carrano

Journal:

Environmental and Molecular Mutagenesis

Year:

1991

Language:

english

File:

PDF, 652 KB

english, 1991

11

Genetic toxicology association—Fall Meeting 1982

Michael J. Skinner, Gary A. Sega, Byron E. Butterworth

Journal:

Journal of Applied Toxicology

Year:

1983

Language:

english

File:

PDF, 281 KB

english, 1983

12

Comparison of chloroform-induced toxicity in the kidneys, liver, and nasal passages of male Osborne-Mendel and F-344 rats

Michael V. Templin, Keith C. Jamison, Douglas C. Wolf, Kevin T. Morgan, Byron E. Butterworth

Journal:

Year:

1996

Language:

english

File:

PDF, 787 KB

english, 1996

13

Induction of micronuclei in wild-type and p53+/− transgenic mice by inhaled bromodichloromethane

Vincent R Torti, Alison J Cobb, Victoria A Wong, Byron E Butterworth

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2002

Language:

english

File:

PDF, 83 KB

english, 2002

14

Dinitrotoluene: Acute Toxicity, Oncogenicity, Genotoxicity, and Metabolism

Rickert, Douglas E., Butterworth, Byron E., Popp, James A., Krahn, David F.

Journal:

Critical Reviews in Toxicology

Year:

1984

Language:

english

File:

PDF, 1.31 MB

english, 1984

15

The integrity of the human gene pool

Byron E. Butterworth

Journal:

Environmental and Molecular Mutagenesis

Year:

1996

Language:

english

File:

PDF, 153 KB

english, 1996

16

Pathogen inactivation of RBCs: PEN110 reproductive toxicology studies

John R. Chapman, Kristen Moore, Byron E. Butterworth

Journal:

Transfusion (Wiley)

Year:

2003

Language:

english

File:

PDF, 100 KB

english, 2003

17

Induction of DNA repair in human and rat hepatocytes by 1,6-dinitropyrene

Byron E. Butterworth, L. Lynn Earle, Stephen Strom, Randy Jirtle, George Michalopoulos

Journal:

Mutation Research Letters

Year:

1983

Language:

english

File:

PDF, 410 KB

english, 1983

18

A 90-Day Chloroform Inhalation Study in F-344 Rats: Profile of Toxicity and Relevance to Cancer Studies

TEMPLIN, MICHAEL V., LARSON, JEFFREY L., BUTTERWORTH, BYRON E., JAMISON, KEITH C., LEININGER, JOEL R., MERY, STEPHANE, MORGAN, KEVIN T., WONG, BRIAN A., WOLF, DOUGLAS C.

Journal:

Toxicological Sciences

Year:

1996

Language:

english

File:

PDF, 5.21 MB

english, 1996

19

Virus-Specific Proteins Synthesized in Encephalomyocarditis Virus-Infected HeLa Cells

Byron E. Butterworth, Linda Hall, C. Martin Stoltzfus and Roland R. Rueckert

Journal:

Proceedings of the National Academy of Sciences

Year:

1971

Language:

english

File:

PDF, 1.06 MB

english, 1971

20

Assessment of chemically-induced DNA repair in rat tracheal epithelial cells

Doolittle, David J., Butterworth, Byron E.

Journal:

Year:

1984

Language:

english

File:

PDF, 1.76 MB

english, 1984

21

Differential display identified changes in mRNA levels in regenerating livers from chloroform-treated mice

Alma E. Kegelmeyer, Catherine S. Sprankle, Gregory J. Horesovsky, Byron E. Butterworth

Journal:

Molecular Carcinogenesis

Year:

1997

Language:

english

File:

PDF, 197 KB

english, 1997

22

Induced Cytolethality and Regenerative Cell Proliferation in the Livers and Kidneys of Male B6C3F1 Mice Given Chloroform by Gavage

Jeffrey L. Larson, Douglas C. Wolf, Byron E. Butterworth

Journal:

Fundamental and Applied Toxicology

Year:

1994

File:

PDF, 451 KB

1994

23

Levels of myc, fos, Ha-ras, met and hepatocyte growth factor mRNA during regenerative cell proliferation in female mouse liver and male rat kidney after a cytotoxic dose of chloroform

Catherine S. Sprankle, Jeffrey L. Larson, Susan M. Goldsworthy, Byron E. Butterworth

Journal:

Year:

1996

Language:

english

File:

PDF, 1.77 MB

english, 1996

24

Biologically based dose response model for hepatic toxicity: a mechanistically based replacement for traditional estimates of noncancer risk

Rory B. Conolly, Byron E. Butterworth

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 576 KB

english, 1995

25

Role of gut flora in the genotoxicity of dinitrotoluene

Mirsalis, Jon C., Hamm, Thomas E., Sherrill, J. Michael, Butterworth, Byron E.

Journal:

Year:

1982

File:

PDF, 266 KB

1982

26

The Toxicity of 1-Week Exposures to Inhaled Chloroform in Female B6C3F 1 Mice and Male F-344 Rats

LARSON, JEFFREY L., WOLF, DOUGLAS C., MORGAN, KEVIN T., MÉRY, STÉPHANE, BUTTERWORTH, BYRON E.

Journal:

Toxicological Sciences

Year:

1994

Language:

english

File:

PDF, 19.66 MB

english, 1994

27

Disinfection By-Products in Drinking Water: Critical Issues in Health Effects Research

John Fawell, Denise Robinson, Richard Bull, Linda Birnbaum, Gary Boorman, Byron Butterworth, Phillippe Daniel, Hend Galal-Gorchev, Fred Hauchman, Päivi Julkunen, Curtis Klaassen, Stuart Krasner, Jenni

Journal:

Environmental Health Perspectives

Year:

1997

Language:

english

File:

PDF, 172 KB

english, 1997

28

Consideration of both genotoxic and nongenotoxic mechanisms in predicting carcinogenic potential

Byron E. Butterworth

Journal:

Mutation Research/Reviews in Genetic Toxicology

Year:

1990

Language:

english

File:

PDF, 1.43 MB

english, 1990

29

A classification framework and practical guidance for establishing a mode of action for chemical carcinogens

Byron E. Butterworth

Journal:

Regulatory Toxicology and Pharmacology

Year:

2006

Language:

english

File:

PDF, 338 KB

english, 2006

30

P XV.9 - P XV.9 Dimethylnitrosamine and chloroform induced mutagenic profiles in lacI transgenic B6C3F1 mice over 180 days

Byron Butterworth, Catherine Sprankle, Michael Templin, Alex Constan, Douglas Wolf, Linda Pluta, Brian Wong, Leslie Recio

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 131 KB

english, 1997

31

A mechanism-based cancer risk assessment for 1,4-dichlorobenzene

Byron E. Butterworth, Lesa L. Aylward, Sean M. Hays

Journal:

Regulatory Toxicology and Pharmacology

Year:

2007

Language:

english

File:

PDF, 202 KB

english, 2007

32

A 90-Day Chloroform Inhalation Study in Female and Male B6C3F1Mice: Implications for Cancer Risk Assessment

Jeffrey L. Larson, Michael V. Templin, Douglas C. Wolf, Keith C. Jamison, Joel R. Leininger, Stephane Méry, Kevin T. Morgan, Brian A. Wong, Rory B. Conolly, Byron E. Butterworth

Journal:

Fundamental and Applied Toxicology

Year:

1996

Language:

english

File:

PDF, 273 KB

english, 1996

33

Failure of the peroxisome proliferator WY-14,643 to induce unscheduled DNA synthesis in rat hepatocytes following in vivo treatment

Cattley, Russell C., Smith-Oliver, Tracey, Butterworth, Byron E., Popp, James A.

Journal:

Year:

1988

Language:

english

File:

PDF, 510 KB

english, 1988

34

Hepatocyte cell proliferation in mice after inhalation exposure to unleaded gasoline vapor

Tilbury, Lorraine, Butterworth, Byron E., Moss, Owen, Goldsworthy, Thomas L.

Journal:

Journal of Toxicology and Environmental Health

Year:

1993

Language:

english

File:

PDF, 1.04 MB

english, 1993

35

The effect of 2,4-diaminotoluene and isomers of dinitrotoluene on unscheduled dna synthesis in primary rat hepatocytes

Edilberto Bermudez, Deborah Tillery, Byron E. Butterworth

Journal:

Environmental and Molecular Mutagenesis

Year:

1979

Language:

english

File:

PDF, 475 KB

english, 1979

36

Examination of potential mechanisms of carcinogenicity of 1,4-dioxane in rat nasal epithelial cells and hepatocytes

Thomas L. Goldsworthy, Thomas M. Monticello, Kevin T. Morgan, Edilberto Bermudez, Daniel M. Wilson, Rudolf Jäckh, Byron E. Butterworth

Journal:

Archives of Toxicology

Year:

1991

Language:

english

File:

PDF, 1022 KB

english, 1991

37

Induced Cytotoxicity and Cell Proliferation in the Hepatocarcinogenicity of Chloroform in Female B6C3F 1 Mice: Comparison of Administration by Gavage in Corn Oil vs ad Libitum in Drinking Water

LARSON, JEFFREY F., WOLF, DOUGLAS C., BUTTERWORTH, BYRON E.

Journal:

Toxicological Sciences

Year:

1994

Language:

english

File:

PDF, 9.88 MB

english, 1994

38

Induced regenerative cell proliferation in livers and kidneys of male F-344 rats given chloroform in corn oil by gavage or ad libitum in drinking water

Jeffrey L. Larson, Douglas C. Wolf, Byron E. Butterworth

Journal:

Year:

1995

Language:

english

File:

PDF, 1.77 MB

english, 1995

39

A 90-Day Chloroform Inhalation Study in Female and Male B6C3F 1 Mice: Implications for Cancer Risk Assessment

LARSON, JEFFREY L., TEMPLIN, MICHAEL V., WOLF, DOUGLAS C., JAMISON, KEITH C., LEINNINGER, JOEL R., MÈRY, STEPHANE, MORGAN, KEVIN T., WONG, BRAIN A., CONOLLY, RORY B., BUTTERWORTH, BYRON E.

Journal:

Toxicological Sciences

Year:

1996

Language:

english

File:

PDF, 5.18 MB

english, 1996

40

Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 mice

Byron E. Butterworth, Michael V. Templin, Alexander A. Constan, Catherine S. Sprankle, Brian A. Wong, Linda J. Pluta, Jeffrey I. Everitt, Leslie Recio

Journal:

Environmental and Molecular Mutagenesis

Year:

1998

Language:

english

File:

PDF, 161 KB

english, 1998

41

Relationship between DNA adduct formation and unscheduled DNA synthesis (UDS) in cultured mouse epidermal keratinocytes

Rosalynn D. Gill, Byron E. Butterworth, Anusha N. Nettikumara, John Digiovanni, J. R. Landolph

Journal:

Environmental and Molecular Mutagenesis

Year:

1991

Language:

english

File:

PDF, 660 KB

english, 1991

42

Metabolism of Chloroform by Cytochrome P450 2E1 Is Required for Induction of Toxicity in the Liver, Kidney, and Nose of Male Mice

Alexander A. Constan, Catherine S. Sprankle, Jeffrey M. Peters, Gregory L. Kedderis, Jeffrey I. Everitt, Brian A. Wong, Frank L. Gonzalez, Byron E. Butterworth

Journal:

Toxicology and Applied Pharmacology

Year:

1999

Language:

english

File:

PDF, 80 KB

english, 1999

43

Assessment of chemically induced DNA repair in primary cultures of human bronchial epithelial cells

David J. Doolittle, James W. Furlong, Byron E. Butterworth

Journal:

Toxicology and Applied Pharmacology

Year:

1985

Language:

english

File:

PDF, 2.63 MB

english, 1985

44

The role of regenerative cell proliferation in chloroform-induced cancer

Byron E. Butterworth, Michael V. Templin, Susan J. Borghoff, Rory B. Conolly, Gregory L. Kedderis, Douglas C. Wolf

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 430 KB

english, 1995

45

Nongenotoxic carcinogens in the regulatory environment

Butterworth, Byron E.

Journal:

Regulatory Toxicology and Pharmacology

Year:

1989

Language:

english

File:

PDF, 1.11 MB

english, 1989

46

Mitogenic stimulation of hepatocellular proliferation in rodents following 1,4-dichlorobenzene administration

Eldridge, Sandra R., Goldsworthy, Thomas L., Popp, James A., Butterworth, Byron E.

Journal:

Year:

1992

Language:

english

File:

PDF, 3.02 MB

english, 1992

47

The Toxicity of 1-Week Exposures to Inhaled Chloroform in Female B6C3F1 Mice and Male F-344 Rats

Jeffrey L. Larson, Douglas C. Wolf, Kevin T. Morgan, Stéphane Méry, Byron E. Butterworth

Journal:

Fundamental and Applied Toxicology

Year:

1994

File:

PDF, 3.43 MB

1994

48

Possible Mechanisms in Hepatocarcinogensis by the Peroxisome Proliferator Di(2-Ethylhexyl)Phthalate

Conway, James G., Cattley, Russell C., Popp, James A., Butterworth, Byron E.

Journal:

Drug Metabolism Reviews

Year:

1989

Language:

english

File:

PDF, 2.16 MB

english, 1989

49

Contamination Is a Frequent Confounding Factor in Toxicology Studies with Anthraquinone and Related Compounds

Butterworth, Byron, Mathre, Owen, Ballinger, Kenneth, Adalsteinsson, Orn

Journal:

International Journal of Toxicology

Year:

2004

Language:

english

File:

PDF, 101 KB

english, 2004

50

Acute Hepatotoxic and Nephrotoxic Effects of Chloroform in Male F-344 Rats and Female B6C3F1 Mice

LARSON, JEFFREY L., WOLF, DOUGLAS C., BUTTERWORTH, BYRON E.

Journal:

Toxicological Sciences

Year:

1993

Language:

english

File:

PDF, 12.79 MB

english, 1993

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